發表論文
期刊論文
Completed Publications in Scientific Journals
Peer Reviewed
- Yu-Jie Su, Pei-Lu Yi, Fang-Chia Chang*. Transcranial direct current stimulation (tDCS) ameliorates stress-induced sleep disruption via activating infralimbic cortex-ventrolateral preoptic area projections. Brain Sciences 2024; 14(1):105 DOI:10.3390/brainsci14010105 (SCI)
- Yun Lo, Pei-Lu Yi, Yi-Tse Hsiao, Tung-Yen Lee, Fang-Chia Chang*. A prolonged stress rat model recapitulates some PTSD-like changes in sleep and neuronal connectivity. Communications Biology 2023; 6:716; https://doi.org/10.1038/s42003-023-05090-9 (SCI).
- Tung-Yen Lee, Pei-Lu Yi, Fang-Chia Chang*. Hypocretin role in posttraumatic stress disorder-like behaviors induced by a novel stress protocol in mice. Frontiers in Psychiatry 2023; 14:1196994; https://doi.org/10.3389/fpsyt.2023.1196994 (SCI).
- Bipasha Nath, Shen-Yu Peng, Zu-Jia Lo, Yu-Hsuan Pai, Yi-Ting Yeh, Huang-Hsiang ChangYi-Ching Lu, Shu-Hui Huang, Fang-Chia Chang. A biphasic current-mode stimulator integrated circuit with a novel residual charge compensation mechanism. Integration 2023; 91: 79-88; https://doi.org/10.1016/j.vlsi.2023.03.003 (SCI).
- Yun Lo, Pei-Lu Yi, Yi-Tse Hsiao, Fang-Chia Chang*. Hypocretin in locus coeruleus and dorsal raphe nucleus mediates inescapable footshock stimulation (IFS)-induced REM sleep alteration. Sleep 2022; 45(3): zsab301; https://doi.org/10.1093/sleep/zsab301 (SCI).
- Yun Lo, Yi-Tse Hsiao, Fang-Chia Chang*. Use electroencephalogram entropy as an indicator to detect stress-induced sleep alteration. Applied Sciences 2022; 12(10): 4812; https://doi.org/10.3390/app12104812 (SCI).
- I-Chen Li, Fang-Chia Chang#, Ching-Chuan Kuo, Hsin-Tung Chu, Tsung-Ju Li, Chin-Chu Chen. Pilot study: Nutritional and preclinical safety investigation of fermented hispidin-enriched Sanghuangporus sanhuang mycelia: a promising functional food material to improve sleep. Frontiers in Nutrition 2022; 8: 788965; https://doi.org/10.3389/fnut.2021.788965 (SCI).
- Tsung-Ju Li, Tung-Yen Lee, Yun Lo, Li-Ya Lee, I-Chen Li, Chin-Chu Chen, Fang-Chia Chang*. Hericium erinaceus mycelium ameliorate anxiety induced continuous sleep disturbance in vivo. BMC Complementary Medicine and Therapy 2021; 21: 295 (SCI).
- Chung-Yao Hsu, Yao-Chung Chuang, Fang-Chia Chang, Hung-Yi Chuang,
Terry Ting-Yu Chiou, Chien-Te Lee. Disrupted sleep homeostasis and altered expressions of clock genes in rats with chronic lead exposure. Toxics 2021; 9:217 (SCI). - Shih-Yin Ho, Li Lin, I-Chun Chen, Che-Wen Tsai, Fang-Chia Chang, Horng-Huei Liou. Perampanel Reduces Hyperthermia-Induced Seizures in Dravet Syndrome Mouse Model. Frontiers in Pharmacology 2021; 12:682767. doi: 10.3389/fphar.2021.682767 (SCI).
- I-Chen Li, Ting-Wei Lin, Tung-Yen Lee, Yun Lo, Yih-Min Jiang, Yu-Hsuan Kuo, Chin-Chu Chen, Fang-Chia Chang*. Oral delivered Armillaria mellea promotes non-rapid eye movement and rapid eye movement sleep in rats. Journal of Fungi 2021; 7(5): 371 (SCI).
12 Yi-Tse Hsiao, Ta-Ching Chen, Pin-Huan Yu, Ding-Siang Huang, Fung-Rong Hu, Cheng-Ming Chuong, Fang-Chia Chang*. Connectivity between nidopallium caudolateral and visual pathways in color perception of zebra finches. Scientific Reports 2020; 10: 19382; DOI: https://doi.org/10.1038/s41598-020-76542-z (SCI).
13 Shuo-Bin Jou, Chung-Jen Tsai, Chun-Ying Fang, Pei-Lu Yi, Fang-Chia Chang*. Effects of N6-(4-hydroxybenzyl) adenine riboside in stress-induced insomnia in rodents. Journal of Sleep Research 2020; DOI: 10.1111/jsr13156 (SCI).
14 Hsin-Tzu Tseng, Yi-Tze Hsiao, Pei-Lu Yi, Fang-Chia Chang*. Deep brain stimulation (DBS) increases epilepsy threshold by altering REM sleep and delta powers during NREM sleep. Frontiers in Neurology 2020; DOI: 10.3389/fneur.2020.00752 (SCI).
15 Yi-Tse Hsiao, Yun Lo, Pei-Lu Yi, Fang-Chia Chang*. Hypocretin in median raphe nucleus modulates footshock stimuli-induced REM sleep alteration. Scientific Reports 2019; 9: 8198 (SCI).
16 Fang-Chia Chang, Pei-Lu Yi, Jaung-Geng Lin. Chapter 11: Acupuncture on Sleep Regulation, Jaung-Geng Lin (ed). Experimental Acupuncturology, Springer Nature: Singapore, 2018.
17 Mu-Lien Lin, Tzu-Rung Huang, Ming-Chien Kao, Hung-Wei Chiu, Sheng-Chieh Lin, Fang-Chia Chang*. Pulse radiofrequency stimulation suppresses palmar hyperhidrosis in an animal study. Brain and Behavior 2017; 7(11): e00833 (SCI)
18 Pei-Lu Yi, Shuo-Bin Jou, Yi-Jou Wu, Fang-Chia Chang*. Manipulation of epileptiform ECoGs and sleep in rats and mice by acupuncture. Journal of Visualized Experiments 2016; 118: e54896; doi: 10.3791/54896. (SCI)
19 Tzu-Rung Huang, Shuo-Bin Jou, Yu-Ju Chou, Pei-Lu Yi, Chun-Jen Chen, Fang-Chia Chang*. Interleukin-1 receptor (IL-1R) mediates epilepsy-induced sleep disruption. BMC Neuroscience 2016; 17:74. (SCI)
20 Hsiao J., T. Y. Yuan, M. S. Tsai, C. Y. Lu, Y. C. Lin, M. L. Lee, S. W. Lin, F. C. Chang, Pimentel H. Liu, C. Olive, C. Coito, G. Shen, M. Young, T. Thorne, M. Lawrence, M. Magistri, M. A. Faghihi, O. Khorkova, and C. Wahlestedt. Upregulation of Haploinsufficient Gene Expression in the Brain by Targeting a Long Non-coding RNA Improves Seizure Phenotype in a Model of Dravet Syndrome. EBioMedicine 2016; 9:257-277. (SCI)
21 Liu C. M., F. C. Chang, and C. T. Lin. Retrospective study of the clinical effects of acupuncture on cervical neurological diseases in dogs. Journal of Veterinary Science 2016; 17(3):337-345. (SCI)
22 Tsai M.S., Lee M.L., Chang C.Y., Fan H.H., Yu I.S., Chen Y.T., You J.Y., Chen C.Y., Chang F.C., Hsiao J.H., Khorkova O., Liou H.H., Yanagawa Y., Lee L.J., Lin S.W. Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a nutant Dravet syndrome model during development. Neurobiology of Disease 2015; 77:35-48. (SCI)
23 Pei-Lu Yi, Chin-Yu Lu, Shuo-Bin Jou, Fang-Chia Chang*. Low-frequency electroacupuncture suppresses focal epilepsy and improves epilepsy-induced sleep disruptions. Journal of Biomedical Science 2015; 22:49. (SCI)
24 Wei-Ta Chen, Fang-Chia Chang, Yi-Jung Chen, Jaung-Geng Lin. An evaluation of electroacupuncture at the Weizhong acupoint (BL-40) as a means of relieving pain induced by extracorporeal shock wave lithotripsy. Evidence-based Complementary and Alternative Medicine 2014; Article ID592319. (SCI)
25 Pei-Lu Yi, Chin-Yu Lu, Chiung-Hsiang Cheng, Yi-Fong Tsai, Chung-Tien Lin, Fang-Chia Chang*. Amygdala opioid receptors mediate the electroacupuncture-induced deterioration of sleep disruptions in epilepsy rats. Journal of Biomedical Science 2013; 20:85. (SCI)
26 Pei-Lu Yi, Chin-Yu Lu, Chiung-Hsiang Cheng, Yi-Fong Tsai, Chung-Tien Lin, Fang-Chia Chang*. Activation of amygdala opioid receptors by electroacupuncture of Feng-Chi (GB20) acupoints exacerbates focal epilepsy. BMC Complementary and Alternative Medicine 2013; 13:290. (SCI)
27 Yi-Tse Hsiao, Pei-Lu Yi, Chiung-Hsiang Cheng, Fang-Chia Chang*. Disruption of footshock-induced theta rhythms by stimulating median raphe nucleus reduces anxiety in rats. Behavioural Brain Research 2013; 247:193-200. (SCI)
28 Shuo-Bin Jou, I-Feng Kuo, Pei-Lu Yi, Fang-Chia Chang*. Electrical stimulation of left anterior thalamic nucleus with high-frequency and low-intensity currents reduces the rate of pilocarpine-induced epilepsy in rats. Seizure 2013; 22:221-229. (SCI)
29 Yi-Tse Hsiao, Chiung-Hsiang Cheng, Pei-Lu Yi, Fang-Chia Chang*. GABAergic neurons in the median raphe nucleus (MRN) modulate footshock-induced rapid eye movement (REM) sleep disturbance in rats. Taiwan Veterinary Journal 2013; 39(1):27-38.
30 Pei-Lu Yi, Ying-Ju Chen, Chung-Tien Lin, Fang-Chia Chang*. Occurrence of epilepsy at different zeitgeber times alters sleep homeostasis differently in rats. Sleep 2012; 35(12):1651-1665. (SCI)
31 Chung-Yao Hsu, Fang-Chia Chang*, Hwee-Yeong Ng, Chien-Chun Kuo, Yueh-Ting Lee, Chin-Yu Lu, Chien-Te Lee. Disrupted circadian rhythm in rats with nephrectomy-induced chronic kidney disease. Life Sciences 2012; 91:127-131. (SCI)
32 Yi-Tse Hsiao, Shuo-Bin Jou, Pei-Lu Yi, Fang-Chia Chang*. Activation of GABAergic pathway by hypocretin in the median raphe nucleus (MRN) mediates stress-induced theta rhythm in rats. Behavioural Brain Research 2012; 233:224-231. (SCI)
33 Chiung-Hsiang Cheng, Pei-Lu Yi, Han-Han Chang, Fang-Chia Chang*. Morphology alterations of synapses in the ventromedial nucleus (VM) of thalamus and caudal nucleus tractus solitarius (NTS) after 10 Hz electroacupuncture in rats. Taiwan Veterinary Journal 2012; 38(2):75-83.
34 Yi-Tse Hsiao, Pei-Lu Yi, Chia-Ling Li, Fang-Chia Chang*. Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats. Neuropharmacology 2012; 62:373-384. (SCI)
35 Chiung-Hsiang Cheng, Pei-Lu Yi, Han-Han Chang, Yi-Fong Tsai, Fang-Chia Chang*. Kappa-opioid receptors in the caudal nucleus tractus solitarius (NTS) mediate 100 Hz electroacupuncture-induced sleep activities in rats. Evidence-based Complementary and Alternative Medicine 2012; Article ID715024, doi: 10.1155/2012/715024. (SCI)
36 Fang-Chia Chang*. Effects of traditional Chinese medicine in insomnia treatment: the possible physiological mechanisms. In: Leon V. Berhardt, editor. Advances in Medicine and Biology: Volume 22. Nova Science Publishers:New York, 2011; Chapter 3.
37 Han-Han Chang, Pei-Lu Yi, Chiung-Hsiang Cheng, Chin-Yu Lu, Yi-Tse Hsiao, Yi-Fong Tsai, Chia-Ling Li, Fang-Chia Chang*. Biphasic effects of baicalin, an active constituent of Scutellaria baicalensis Georgi, in the spontaneous sleep-wake regulation. Journal of Ethnopharmacology 2011; 135:359-368. (SCI)
38 Chiung-Hsiang Cheng, Pei-Lu Yi, Jaung-Geng Lin, Fang-Chia Chang*. Endogenous opiates in the nucleus tractus solitaries mediate electroacupuncture-induced sleep activities in rats. Evidence-based Complementary and Alternative Medicine 2011; Article ID159209, doi: 10.1093/ecam/nep132. (SCI)
39 Chiung-Hsiang Cheng, Yun-Feng Ku, Chun-Han Hou, Lih-Seng Yeh, and Fang-Chia Chang*. Nerve re-innervations by an end-to-side neurorrhaphy of myocutaneous transplantation in rats. Taiwan Veterinary Journal 2011; 37(3):143-151.
40 Han-Han Cang, Chiung-Hsiung Cheng, Pei-Lu Yi, Chin-Yu Lu, Yi-Fong Tsai, Yi-Tse Hsiao, Fang-Chia Chang*. Biphasic effects of wogonin in the regulation of spontaneous sleep. Taiwan Veterinary Journal 2011;37 (3):180-190.
41 Jong-Hang Chen, Tong-Rong Jan, Fang-Chia Chang, Chin-Chen Chou. Metabolism, neurotoxicity, and food safety influences of acrylamide. Taiwan Veterinary Journal 2011; 37(1):63-73.
42 Chin-Yu Lu, Pei-Lu Yi, Chon-Haw Tsai, Chiung-Hsiang Cheng, Han-Han Chang, Yi-Tse Hsiao, Fang-Chia Chang*. TNF-NF-kB signaling mediates excessive somnolence in hemiparkinsonian rats. Behavioural Brain Research 2010; 208:484-496. (SCI)
43 Fang-Chia Chang*. Minireview: canine insomnia. Journal of Veterinary Clinical Sciences 2009; 2(4):100-107.
44 Shiaw-Pyng Wey, Hsin-Ying Wu, Fang-Chia Chang, Tong-Rong Jan. Methamphetamine and diazepam suppress antigen-specific cytokine expression and antibody production in ovalbumin-sensitized BALB/c mice. Toxicology Letters 2008; 181:157-162. (SCI)
45 Pei-Lu Yi, Yi-Tes Hsiao, Chon-Haw Tsai, Tong-Rong Jan, Chin-Yu Lu, Fang-Chia Chang*. Serotonergic system in the central nucleus of amygdala mediates cannabidiol-induced sleep alteration. The Open Sleep Journal 2008; 1:58-68.
46 Ming-Kuei Lu, Hsu-Tzu Shih, Kai-Ju Huang, Ulf Ziemann, Chon-Haw Tsai, Fang-Chia Chang*, Ya-Chu Chen, Yi-Tsung Lin, Wei-Shih Huang, Cheng-Chun Lee, Chin-San Liu. Movement-related cortical potential in patients with Machado-Joseph disease. Clinical Neurophysiology 2008; 119:1010-1019. (SCI)
47 Pei-Lu Yi, Chun-Pang Lin, Chon-Haw Tsai, Jaung-Geng Lin & Fang-Chia Chang*. The involvement of serotonin receptors in suanzaorentang-induced sleep alteration. Journal of Biomedical Science 2007; 14:829-840. (SCI)
48 Pei-Lu Yi, Chon-Haw Tsai, Ming-Kuei Lu, Hsu-Jan Liu, Ya-Chu Chen, Fang-Chia Chang*. Interleukin-1b mediates sleep alteration in rats with rotenone-induced parkinsonism. Sleep 2007; 30(4):413-425. (SCI)
49 Pei-Lu Yi, Chon-Haw Tsai, Ya-Chu Chen, Fang-Chia Chang*. Gamma-aminobutyric acid (GABA) receptor mediates suanzaorentang, a traditional Chinese herb remedy, -induced sleep alteration. Journal of Biomedical Science 2007; 14:258-297. (SCI)
50 Ming-Kuei Lu, Fang-Chia Chang, Yu-Wan Yang, Yu-Chin Lin, Cheng-Chun Lee, Chon-Haw Tsai. Abnormal movement-related cortical potential in patients with subcortical heterotopia. Brain & Development 2006; 28:560-565. (SCI)
51 Yu-Wan Yang, Chon-Haw Tsai, Fang-Chia Chang, Ming-Kuei Lu, Paiyi Chiu. Reversible paraneoplastic limbic encephalitis caused by a benign ovarian teratoma: report of a case and review of literatures. Journal of Neuro-Oncology 2006; 80:309-312. (SCI)
52 CH Tsai, FC Chang, YT Huang, RS Chen, CC Chen, T Wu, YH Weng, SZ Lee, ZD Lee, CY Lieu, HC Chang, MK Lu, CC Lee, CS Lu. Pallidotomy effect on the central excitability in patients with severe Parkinson’s disease. Movement Disorders 2005; 20(4):463-470. (SCI)
53 Yu-Wan Yang, Fang-Chia Chang, Chon-Haw Tsai, Jui-Chen Wu, Chin-Song Lu, Chi-Chung Juo, Ming-Kuei Lu, Wei-Liang Chen, Chen-Chun Lee. Clinical and magnetic resonance imaging manifestations of Holmes tremor. Acta Neurologica Taiwanica 2005; 14(1):9-15. (SCI)
54 Pei-Lu Yi, Chon-Haw Tsai, Jaung-Geng Lin, Hsu-Jan Liu and Fang-Chia Chang*. Effects of electroacupuncture of “Anmian” acupoints on sleep activities in rats: the implication of caudal nucleus tractus solitarius. Journal of Biomedical Science 2004; 11:579-590. (SCI)
55 Pei-Lu Yi, Chon-Haw Tsai, Ming-Kuei Lu, Ya-Ju Chen, Yu-Wan Yang and Fang-Chia Chang*. The effects of a brief light pulse and intracerebroventricular injection on sleep-wake activity in rats, Mid-Taiwan Journal of Medicine. 2004; 9(4):211-218.
56 Pei-Lu Yi, Mark R. Opp, Fang-Chia Chang*. Increase of corticotropin-releasing hormone (CRH) in the central nervous system mediates stressors-induced sleep alteration, Mid-Taiwan Journal of Medicine 2004; 9(3):80-86.
57 Pei-Lu Yi, Chon-Haw Tsai, Jaung-Geng Lin, Cheng-Chun Lee and Fang-Chia Chang*. Kindling stimuli delivered at different times in the sleep-wake cycle. Sleep 2004; 27(2):203-212. (SCI)
58 Fang-Chia Chang, Huei-Yann Tsai, Ming-Chien Yu, Pei-Lu Yi, and Jaung-Geng Lin. Central serotonergic system mediates analgesic effect of electroacupuncture on Zusanli (ST36) acupoint. Journal of Biomedical Science 2004; 11:179-185. (SCI)
59 CH Tsai, FC Chang, YC Su, FJ Tsai, MK Lu, CC Lee, CC Kuo, YW Yang, CS Lu. Two novel mutations of the glycine receptor gene and electrophysiological manifestation in a family with autosomal recessive hereditary hypereklpexia. Neurology 2004; 63(5):893-896. (SCI)
60 Fang-Chia Chang and Mark R. Opp. A corticotropin-releasing hormone antisense oligodeoxynucleotide reduces spontaneous waking in the rats. Regulatory Peptides 2004; 117(1):43-52. (SCI)
61 PC Tsai, FC Chang, CH Tsai, FR Jang, AN Shen, YT Huang, SC Lai, TH Yeh, MK Lu, CS Lu. Focal hand myoclonus caused by a small hematoma underneath the cerebral motor cortex. European Neurology 2003; 50:114-117. (SCI)
62 Tzung-Chang Tsai, Jer-Yuam Wu, Cheng-Chung Lee, Chon-Haw Tsai, Fuu-Jen Tsai, Fang-Chia Chang, Chi-Chung Kuo. No association between the dopamine transproter gene polymorphism and sporadic Parkinson’s disease among Chinese in Taiwan. Mid-Taiwan Journal of Medicine 2003; 8(Supplement 2):S75-8.
63 Fang-Chia Chang and Mark R. Opp. The role of corticotropin-releasing hormone (CRH) in stressor-induced alterations of sleep in the rat. American Journal of Physiology 2002; 283:R400-R407. (SCI)
64 C.H. Tsai, S.K. Lo, L.C. See, H.Z. Chen, R.S. Chen, Y.H. Weng, F.C. Chang, CS Lu. Environmental risk factors of young onset Parkinson’s disease: a case-control study. Clinical Neurology and Neurosurgery 2002; 104:328-333. (SCI)
65 Fang-Chia Chang* and Mark R. Opp. Corticotropin-releasing hormone (CRH) as a regulator of waking, Neuroscience and Biobehavioral Reviews 2001; 25(5):445-453. (SCI)
66 Fang-Chia Chang and Mark R. Opp. IL-1 is a mediator of increases in slow wave sleep induced by CRH receptor blockade. American Journal of Physiology 2000; 279:R793-R802. (SCI)
67 Fang-Chia Chang and Mark R. Opp. Pituitary CRH receptor blockade reduces waking in the rat. Physiology & Behavior 1999; 67:691-696. (SCI)
68 Fang-Chia Chang and Mark R. Opp. Blockade of corticotropin-releasing hormone (CRH) receptors reduces spontaneous waking in the rat. American Journal of Physiology 1998; 275:R793-R802. (SCI)
69 Pei-Lu Yi, Fang-Chia Chang, Jing-Jane Tsai, Chen-Road Hung and Po-Wu Gean. The involvement of metabotropic glutamate receptors in long-term depression of N-methyl-D-aspartate receptor-mediated synaptic potential in the rat hippocampus. Neuroscience Letters 1995; 185:207-210. (SCI)
70 Po-Wu Gean, Fang-Chia Chang, Pei-Lu Yi, Jju-Home Lin and Jing-Jane Tsai. Activation of metabotropic glutamate receptors in conjunction with postsynaptic depolarization triggers a long-term depression of the N-methyl-D-aspartate receptor-mediated synaptic potential in the rat hippocampus. Journal of Biomedical Science 1995; 2:166-173. (SCI)
71 Po-Wu Gean, Fang-Chia Chang, Chiung-Chun Huang, Jju-Home Lin and Long-Joy Way. Long-term enhancement of EPSP and NMDA receptor-mediated synaptic transmission in the amygdala. Brain Research Bulletin 1993; 31:7-11. (SCI)
72 P.-W. Gean, F.-C. Chang and C.-R. Hung. Use-dependent modification of a slow NMDA receptor-mediated synaptic potential in rat amygdalar slices. Journal of Neuroscience Research 1993; 34:635-641. (SCI)
73 Po-Wu Gean and Fang-Chia Chang. Pharmacological characterization of excitatory synaptic potentials in rat basolateral amygdaloid neurons. Synapse 1992; 11:1-9. (SCI)
74 Po-Wu Gean and Fang-Chia Chang. Ketamine suppresses synchronized discharges in the disinhibited amygdala slice. Brain Research Bulletin 1991; 26:923-927. (SCI)
75 P.-W. Gean and F.-C. Chang. Bursting discharges in disinhibited amygdala slices: the role of excitatory amino acid receptors. Neuropharmacology 1991; 30:797-803. (SCI)
76 Po-Wu Gean, Shui-Mei Chou and Fang-Chia Chang. Epileptiform activity involved by 4-aminopyridine in rat amygdala neurons: the involvement of N-methyl-D-aspartate receptors. European Journal of Pharmacology 1990; 184:213-221. (SCI)